Opioid and Prescription Drugs

School Resources

School Resources

Opioid and Prescription Drugs

Operation Prevention's school resources provide educators with engaging tools that are aligned to national health and science standards, and integrate seamlessly into classroom instruction. Through a series of hands-on investigations, students will explore the science behind substance misuse, and the resulting impacts on our brain and body.

Elementary School

Proactive Prevention


Over-the-Counter and Prescription Medications: How do medications work in our bodies, and why is it so important to use them responsibly? Follow medication on a path through the body to investigate how they make us feel better with responsible use.

Malachi's Medication

Interdisciplinary Activity

In this activity, students will identify and explain the dosage instructions included on a prescription label and conduct an experiment to understand the importance of accurately measuring medication dosage.

Sarah's Sister

Interdisciplinary Activity

In this activity, students will meet Sarah and her younger sister who has gotten hold of medication that was not properly stored, to understand the importance of storing medication safely.

Middle School

Our Brain and Body on Opioids


How do addiction and withdrawal affect the body's many systems? Students examine how drug use alters the mind and body and reinforces their understanding by creating a peer-to-peer social media campaign.

Is our Community Influenced by the Opioid Epidemic?


Students will examine why people turn to opioids and act as investigative reporters to consider the who, what, when, where, why, and how of opioid use and misuse.

High School

Opioid Use:
The Signs. The Symptoms. The Science


Separate fact from fiction with this classroom-ready digital lesson. Through investigation and hands-on activities, students learn the science behind prescription opioid and heroin addiction, overdose, and withdrawal.

Reporting on a Public Health Crisis:
Opioids in the Community


Students will investigate how the opioid epidemic impacts their community acting as investigative reporters to investigate the who, what, when, where, why, and how of opioid use and misuse.

Middle School and High School

Self-Paced Module
What is an Opioid, and how does it affect your body?

The Science of Addiction
The Stories of Teens

In this self-paced, standards-aligned e-learning experience, students meet teens who are struggling with prescription opioid misuse and heroin use and learn the science behind their powerful stories. With strategies and resources for those being faced with a decision about prescription opioid misuse or struggles with addiction, students become better equipped to handle these experiences.

Educator Training

Education Training Staff

To help educators better prepare for conversations with students about the most common forms of substance misuse threatening their communities, this webinar walks through Operation Prevention's new video topic series, which addresses all the primary drug categories.

Additional Resources: Multi-Drug Exploratory

Multi-Drug Exploratory

Empower elementary and middle school students with a science-based background knowledge of the most common forms of substance misuse, along with refusal skills and strategies to support long-term wellbeing. Kickstart life-saving conversations with this easy-to-use digital tool!

Explore Multi-Drug Exploratory